Characterization of -isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis
Alpha-isopropylmalate synthase (-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding -IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repeat...
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Main Authors: | , , |
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Format: | Article |
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2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/27673 |
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Institution: | Mahidol University |