Characterization of -isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis

Alpha-isopropylmalate synthase (-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding -IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repeat...

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Bibliographic Details
Main Authors: Wandee Yindeeyoungyeon, Supaporn Likitvivatanavong, Prasit Palittapongarnpim
Other Authors: Thailand National Center for Genetic Engineering and Biotechnology
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27673
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Institution: Mahidol University