Hyponatremia in severe malaria: Evidence for an appropriate anti-diuretic hormone response to hypovolemia

• Main Authors: Josh Hanson, Amir Hossain, Prakaykaew Charunwatthana, Mahtab Uddin Hassan, Timothy M.E. Davis, Sophia W.K. Lam, S. A.Paul Chubb, Richard J. Maude, Emran Bin Yunus, Gofranul Haque, Nicholas J. White, Nicholas P.J. Day, Arjen M. Dondorp
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27751

Although hyponatremia occurs in most patients with severe malaria, its pathogenesis, prognostic significance, and optimal management have not been established. Clinical and biochemical data were prospectively collected from 171 consecutive Bangladeshi adults with severe malaria. On admission, 57% of...