Use of peroxisome proliferator-activated receptor γ agonists as adjunctive treatment for Plasmodium falciparum malaria: A randomized, double-blind, placebo-controlled trial

• Main Authors: Andrea K. Boggild, Srivicha Krudsood, Samir N. Patel, Lena Serghides, Noppadon Taagpukdee, Kevin Katz, Polrat Wilairatana, W. Conrad Liles, Sornchai Looareesuwan, Kevin C. Kain
• Other Authors: Toronto General Hospital
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27932
• Institution: Mahidol University

Background. Despite the use of potent antimalarial drugs, the fatality rate associated with severe malaria remains high. Adjunctive therapies that target the immunopathological responses to infection may decrease mortality associated with severe malaria. We hypothesized that peroxisome proliferator-...