Blood stage plasmodium falciparum antigens induce immunoglobulin class switching in human enriched b cell culture
This study aimed to demonstrate class switch recombination (CSR) in heavy chain expressing immunoglobulin G (IgG) and IgE in human B cells after exposure to Plasmodium falciparum schizont lysate. Human B cells (CD20 +CD27 -) were cultured with crude P. falciparum antigen (cPfAg) and anti-CD40. On Da...
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Main Authors: | , , , , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/28031 |
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Institution: | Mahidol University |