Isolation and Characterization of 3β-lup-20(29)-en-3-ol (Lupeol) from the Leaves and Twigs of Diospyros phuketensis Phengklai

Diospyros is one of most important genus of the Ebenceae family. The pharmacological activities, bio-assays and chemical constituent of various Diospyros extracts have been reviewed by various research groups. Lupeol, a pentacyclic lupane-type, has been discovered in over 90% of the Diospyros spec...

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Main Authors: ณัฐพัชร์ สังเฉวก, สุทธิพร พิกุลทอง, Natthapat Sugchawek, Suttiporn Pikultong
Other Authors: มหาวิทยาลัยมหิดล. คณะวิทยาศาสตร์. ภาควิชาเคมี
Format: Article
Language:Thai
Published: 2017
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/2821
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Institution: Mahidol University
Language: Thai
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Summary:Diospyros is one of most important genus of the Ebenceae family. The pharmacological activities, bio-assays and chemical constituent of various Diospyros extracts have been reviewed by various research groups. Lupeol, a pentacyclic lupane-type, has been discovered in over 90% of the Diospyros species. Its biological activities have been reported as being anti-inflammatory, anti-arthritic and anti-mutagenic, both in vitro and in vivo systems. Herein, lupeol is found for the first time from the leaves and twigs of Diospyros Phuketensis Phengkai which have never been reported. Column chromatography of the extract gave lupeol confirmed structure by mass spectrometry IR and NMR data.