Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: An electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines

Little is known about how amyloid-β (Aβ) is deposited in relation to the complex ultrastructure of the brain. Here we combined serial section immunoelectron microscopy with 3D reconstruction to elucidate the spatial relationship between Aβ deposits and ultrastructurally identified cellular compartme...

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Bibliographic Details
Main Authors: Paworn Nuntagij, Salvatore Oddo, Frank M. LaFerla, Naiphinich Kotchabhakdi, Ole P. Ottersen, Reidun Torp
Other Authors: Universitetet i Oslo
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/28285
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Institution: Mahidol University