Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: An in vivo study

• Main Authors: Pinpat Tripatara, Nimesh S.A. Patel, Vincenzo Brancaleone, Derek Renshaw, Joao Rocha, Bruno Sepodes, Helder Mota-Filipe, Mauro Perretti, Christoph Thiemermann
• Other Authors: Barts and The London Queen Mary's School of Medicine and Dentistry
• Format: Article
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28327
• Institution: Mahidol University

The generation of endogenous hydrogen sulphide may either limit or contribute to the degree of tissue injury caused by ischaemia/reperfusion injury. Here, we have attempted to characterise the endogenous hydrogen sulphide synthesis pathway and the effects of sodium hydrosulphide, a hydrogen sulphide...