17β-Estradiol protects Schwann cells against H<inf>2</inf>O<inf>2</inf>-induced cytotoxicity and increases transplanted Schwann cell survival in a cervical hemicontusion spinal cord injury model

• Main Authors: Akkradate Siriphorn, Supin Chompoopong, Candace L. Floyd
• Other Authors: University of Alabama at Birmingham
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28609
• Institution: Mahidol University

Schwann cell (SC) transplantation is a promising repair strategy after spinal cord injury (SCI); however, a large number of SCs do not survive following transplantation. Previous studies have shown that 17β-estradiol (E2) protects several cell types against cytotoxicity. Thus, this study evaluated t...