ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner
ATRX is an X-linked gene of the SWI/SNF family, mutations in which cause syndromal mental retardation and downregulation of α-globin expression. Here we show that ATRX binds to tandem repeat (TR) sequences in both telomeres and euchromatin. Genes associated with these TRs can be dysregulated when AT...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/28613 |
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Institution: | Mahidol University |