The ubiquitin-proteasome pathway is important for dengue virus infection in primary human endothelial cells

• Main Authors: Rattiyaporn Kanlaya, Sa Nga Pattanakitsakul, Supachok Sinchaikul, Shui Tein Chen, Visith Thongboonkerd
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28634

Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are the most severe forms of dengue virus infection with hemorrhage and plasma leakage. However, pathogenic mechanisms of DHF and DSS remain poorly understood. We therefore investigated host responses as determined by changes in the cell...