Time to re-appraise the role of alpha-1 adrenoceptor antagonists in the management of hypertension?

• Main Authors: Neil Chapman, Chung Yin Chen, Toshiro Fujita, Fd Richard Hobbs, Soo Joong Kim, Jan A. Staessen, Supachai Tanomsup, Ji Guang Wang, Bryan Williams
• Other Authors: Imperial College London
• Format: Review
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28651
• Institution: Mahidol University

The role of alpha-1 adrenoceptor antagonists (alpha-blockers) in the management of hypertension continues to evolve. Recent data support their use as add-on therapy in uncontrolled hypertension when used in combination with all other major classes of antihypertensive drug and there is increasing evi...