Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera

• Main Authors: Joshua Parks, Thinley Gyeltshen, Vilailak Prachyawarakorn, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop
• Other Authors: Chulabhorn Research Institute
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28706
• Institution: Mahidol University

Three new compounds, a meroterpene (2) having a cyclopropane moiety named globiferane and glutarimide alkaloids named cordiarimides A (3) and B (4), were isolated from the roots of Cordia globifera. Compounds 2-4 exhibited weak cytotoxic activity. Cordiarimide B (4) exhibited radical scavenging acti...