Molecular characterization of Streptococcus mutans strains containing the cnm gene encoding a collagen-binding adhesin

• Main Authors: K. Nakano, R. Nomura, N. Taniguchi, J. Lapirattanakul, A. Kojima, S. Naka, P. Senawongse, R. Srisatjaluk, L. Grönroos, S. Alaluusua, M. Matsumoto, T. Ooshima
• Other Authors: Osaka University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28843
• Institution: Mahidol University

Objective: Streptococcus mutans, known to be a major pathogen of dental caries, is also considered to cause infective endocarditis. Its 120-kDa Cnm protein binds to type I collagen, which may be a potential virulence factor. In this study, we characterized S. mutans clinical strains focusing on the...