The reality of using primaquine

• Main Authors: Kathy L. Burgoine, Germana Bancone, François Nosten
• Other Authors: Shoklo Malaria Research Unit
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/29149
• Institution: Mahidol University

Background: Primaquine is currently the only medication used for radical cure of Plasmodium vivax infection. Unfortunately, its use is not without risk. Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency have an increased susceptibility to haemolysis when given primaquine. This potent...