Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase

Background: We have previously shown that inhaled corticosteroids activate indoleamine 2, 3-dioxygenase (IDO) activity through increased IL-10 secretion. Statins might enhance the anti-inflammatory effects of corticosteroids. Objective: In a double-blind study we added simvastatin to patients with m...

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Bibliographic Details
Main Authors: Kittipong Maneechotesuwan, Wuttichai Ekjiratrakul, Kanda Kasetsinsombat, Adisak Wongkajornsilp, Peter J. Barnes
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29192
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Institution: Mahidol University