Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production

• Main Authors: Pierre Becquart, Nadia Wauquier, Dieudonné Nkoghe, Angélique Ndjoyi-Mbiguino, Cindy Padilla, Marc Souris, Eric M. Leroy
• Other Authors: Centre International de Recherches Medicales de Franceville
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/29343
• Institution: Mahidol University

Background: Dengue is now a leading cause of morbidity and mortality throughout the tropics. We conducted the first ex vivo study of dengue fever (DF) in African patients infected during the first Gabonese dengue virus 2 (DENV-2) outbreak in 2007, in order to investigate cytokine production, includi...