Intrinsic antibody-dependent enhancement of microbial infection in macrophages: Disease regulation by immune complexes

A wide range of microorganisms can replicate in macrophages, and cell entry of these pathogens via non-neutralising IgG antibody complexes can result in increased intracellular infection through idiosyncratic Fcγ-receptor signalling. The activation of Fcγ receptors usually leads to phagocytosis. Par...

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Bibliographic Details
Main Authors: Scott B. Halstead, Suresh Mahalingam, Mary A. Marovich, Sukathida Ubol, David M. Mosser
Other Authors: University of Canberra
Format: Review
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29875
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Institution: Mahidol University