Acute encephalopathy associated with influenza A infection in adults

We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered w...

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Main Authors: Nelson Lee, Chun Kwok Wong, Paul K.S. Chan, Niklas Lindegardh, Nicholas J. White, Frederick G. Hayden, Edward H.C. Wong, Ka Shing Wong, Clive S. Cockram, Joseph J.Y. Sung, David S.C. Hui
Other Authors: Chinese University of Hong Kong
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29877
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spelling th-mahidol.298772018-09-24T16:38:18Z Acute encephalopathy associated with influenza A infection in adults Nelson Lee Chun Kwok Wong Paul K.S. Chan Niklas Lindegardh Nicholas J. White Frederick G. Hayden Edward H.C. Wong Ka Shing Wong Clive S. Cockram Joseph J.Y. Sung David S.C. Hui Chinese University of Hong Kong Mahidol University University of Oxford University of Virginia Medical School Medicine We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis. 2018-09-24T09:38:17Z 2018-09-24T09:38:17Z 2010-01-01 Article Emerging Infectious Diseases. Vol.16, No.1 (2010), 139-142 10.3201/eid1601.090007 10806059 10806040 2-s2.0-73949099692 https://repository.li.mahidol.ac.th/handle/123456789/29877 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=73949099692&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Nelson Lee
Chun Kwok Wong
Paul K.S. Chan
Niklas Lindegardh
Nicholas J. White
Frederick G. Hayden
Edward H.C. Wong
Ka Shing Wong
Clive S. Cockram
Joseph J.Y. Sung
David S.C. Hui
Acute encephalopathy associated with influenza A infection in adults
description We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
author2 Chinese University of Hong Kong
author_facet Chinese University of Hong Kong
Nelson Lee
Chun Kwok Wong
Paul K.S. Chan
Niklas Lindegardh
Nicholas J. White
Frederick G. Hayden
Edward H.C. Wong
Ka Shing Wong
Clive S. Cockram
Joseph J.Y. Sung
David S.C. Hui
format Article
author Nelson Lee
Chun Kwok Wong
Paul K.S. Chan
Niklas Lindegardh
Nicholas J. White
Frederick G. Hayden
Edward H.C. Wong
Ka Shing Wong
Clive S. Cockram
Joseph J.Y. Sung
David S.C. Hui
author_sort Nelson Lee
title Acute encephalopathy associated with influenza A infection in adults
title_short Acute encephalopathy associated with influenza A infection in adults
title_full Acute encephalopathy associated with influenza A infection in adults
title_fullStr Acute encephalopathy associated with influenza A infection in adults
title_full_unstemmed Acute encephalopathy associated with influenza A infection in adults
title_sort acute encephalopathy associated with influenza a infection in adults
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/29877
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