The Asia-Pacific consensus on ulcerative colitis

Inflammatory bowel disease (IBD) is increasing in many parts of the Asia-Pacific region. There is a need to improve the awareness of IBD and develop diagnostic and management recommendations relevant to the region. This evidence-based consensus focuses on the definition, epidemiology and management...

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Main Authors: Choon Jin Ooi, Kwong Ming Fock, Govind K. Makharia, Khean Lee Goh, Khoon Lin Ling, Ida Hilmi, Wee Chian Lim, Thia Kelvin, Peter R. Gibson, Richard B. Gearry, Qin Ouyang, Jose Sollano, Sathaporn Manatsathit, Rungsun Rerknimitr, Shu Chen Wei, Wai Keung Leung, H. Janaka De Silva, Rupert Wl Leong
Other Authors: Singapore General Hospital
Format: Review
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29890
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spelling th-mahidol.298902018-09-24T16:38:56Z The Asia-Pacific consensus on ulcerative colitis Choon Jin Ooi Kwong Ming Fock Govind K. Makharia Khean Lee Goh Khoon Lin Ling Ida Hilmi Wee Chian Lim Thia Kelvin Peter R. Gibson Richard B. Gearry Qin Ouyang Jose Sollano Sathaporn Manatsathit Rungsun Rerknimitr Shu Chen Wei Wai Keung Leung H. Janaka De Silva Rupert Wl Leong Singapore General Hospital Changi General Hospital All India Institute of Medical Sciences, New Delhi University of Malaya Tan Tock Seng Hospital Monash University University of Otago West China Hospital of Sichuan University University of Santo Tomas, Manila Mahidol University Chulalongkorn University National Taiwan University Chinese University of Hong Kong University of Kelaniya University of New South Wales (UNSW) Australia Medicine Inflammatory bowel disease (IBD) is increasing in many parts of the Asia-Pacific region. There is a need to improve the awareness of IBD and develop diagnostic and management recommendations relevant to the region. This evidence-based consensus focuses on the definition, epidemiology and management of ulcerative colitis (UC) in Asia. A multi-disciplinary group developed the consensus statements, reviewed the relevant literature, and voted on them anonymously using the Delphi method. The finalized statements were reviewed to determine the level of consensus, evidence quality and strength of recommendation. Infectious colitis must be excluded prior to diagnosing UC. Typical histology and macroscopic extent of the disease seen in the West is found in the Asia-Pacific region. Ulcerative colitis is increasing in many parts of Asia with gender distribution and age of diagnosis similar to the West. Extra-intestinal manifestations including primary sclerosing cholangitis are rarer than in the West. Clinical stratification of disease severity guides management. In Japan, leukocytapheresis is a treatment option. Access to biologic agents remains limited due to high cost and concern over opportunistic infections. The high endemic rates of hepatitis B virus infection require stringent screening before initiating immune-suppressive agents. Vaccination and prophylactic therapies should be initiated on a case-by-case basis and in accordance with local practice. Colorectal cancer complicates chronic colitis. A recent increase in UC is reported in the Asia-Pacific region. These consensus statements aim to improve the recognition of UC and assist clinicians in its management with particular relevance to the region. © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. 2018-09-24T09:38:56Z 2018-09-24T09:38:56Z 2010-01-01 Review Journal of Gastroenterology and Hepatology (Australia). Vol.25, No.3 (2010), 453-468 10.1111/j.1440-1746.2010.06241.x 14401746 08159319 2-s2.0-77649226304 https://repository.li.mahidol.ac.th/handle/123456789/29890 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77649226304&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Choon Jin Ooi
Kwong Ming Fock
Govind K. Makharia
Khean Lee Goh
Khoon Lin Ling
Ida Hilmi
Wee Chian Lim
Thia Kelvin
Peter R. Gibson
Richard B. Gearry
Qin Ouyang
Jose Sollano
Sathaporn Manatsathit
Rungsun Rerknimitr
Shu Chen Wei
Wai Keung Leung
H. Janaka De Silva
Rupert Wl Leong
The Asia-Pacific consensus on ulcerative colitis
description Inflammatory bowel disease (IBD) is increasing in many parts of the Asia-Pacific region. There is a need to improve the awareness of IBD and develop diagnostic and management recommendations relevant to the region. This evidence-based consensus focuses on the definition, epidemiology and management of ulcerative colitis (UC) in Asia. A multi-disciplinary group developed the consensus statements, reviewed the relevant literature, and voted on them anonymously using the Delphi method. The finalized statements were reviewed to determine the level of consensus, evidence quality and strength of recommendation. Infectious colitis must be excluded prior to diagnosing UC. Typical histology and macroscopic extent of the disease seen in the West is found in the Asia-Pacific region. Ulcerative colitis is increasing in many parts of Asia with gender distribution and age of diagnosis similar to the West. Extra-intestinal manifestations including primary sclerosing cholangitis are rarer than in the West. Clinical stratification of disease severity guides management. In Japan, leukocytapheresis is a treatment option. Access to biologic agents remains limited due to high cost and concern over opportunistic infections. The high endemic rates of hepatitis B virus infection require stringent screening before initiating immune-suppressive agents. Vaccination and prophylactic therapies should be initiated on a case-by-case basis and in accordance with local practice. Colorectal cancer complicates chronic colitis. A recent increase in UC is reported in the Asia-Pacific region. These consensus statements aim to improve the recognition of UC and assist clinicians in its management with particular relevance to the region. © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
author2 Singapore General Hospital
author_facet Singapore General Hospital
Choon Jin Ooi
Kwong Ming Fock
Govind K. Makharia
Khean Lee Goh
Khoon Lin Ling
Ida Hilmi
Wee Chian Lim
Thia Kelvin
Peter R. Gibson
Richard B. Gearry
Qin Ouyang
Jose Sollano
Sathaporn Manatsathit
Rungsun Rerknimitr
Shu Chen Wei
Wai Keung Leung
H. Janaka De Silva
Rupert Wl Leong
format Review
author Choon Jin Ooi
Kwong Ming Fock
Govind K. Makharia
Khean Lee Goh
Khoon Lin Ling
Ida Hilmi
Wee Chian Lim
Thia Kelvin
Peter R. Gibson
Richard B. Gearry
Qin Ouyang
Jose Sollano
Sathaporn Manatsathit
Rungsun Rerknimitr
Shu Chen Wei
Wai Keung Leung
H. Janaka De Silva
Rupert Wl Leong
author_sort Choon Jin Ooi
title The Asia-Pacific consensus on ulcerative colitis
title_short The Asia-Pacific consensus on ulcerative colitis
title_full The Asia-Pacific consensus on ulcerative colitis
title_fullStr The Asia-Pacific consensus on ulcerative colitis
title_full_unstemmed The Asia-Pacific consensus on ulcerative colitis
title_sort asia-pacific consensus on ulcerative colitis
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/29890
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