Exploring the limits of ultrafast polymerase chain reaction using liquid for thermal heat exchange: A proof of principle
Thermal ramp rate is a major limiting factor in using real-time polymerase chain reaction (PCR) for routine diagnostics. We explored the limits of speed by using liquid for thermal exchange rather than metal as in traditional devices, and by testing different polymerases. In a clinical setting, our...
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Main Authors: | George Maltezos, Matthew Johnston, Konstantin Taganov, Chutatip Srichantaratsamee, John Gorman, David Baltimore, Wasun Chantratita, Axel Scherer |
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Other Authors: | California Institute of Technology |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/29936 |
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Institution: | Mahidol University |
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