Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study

Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study

Electron microscopic examination of intraerythrocytic inclusion bodies induced by methylene blue was carried out in 7 non-splenectomized patients with haemoglobin (Hb) H disease. In classical Hb H disease with the genotype of α-thalassaemia 1/α-thalassaemia 2 the inclusion bodies were mostly membran...

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Main Authors: A. Bunyaratvej, S. Sahaphong, N. Bhamarapravati, P. Wasi
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/30534
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spelling th-mahidol.305342018-10-12T14:36:41Z Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study A. Bunyaratvej S. Sahaphong N. Bhamarapravati P. Wasi Mahidol University Medicine Electron microscopic examination of intraerythrocytic inclusion bodies induced by methylene blue was carried out in 7 non-splenectomized patients with haemoglobin (Hb) H disease. In classical Hb H disease with the genotype of α-thalassaemia 1/α-thalassaemia 2 the inclusion bodies were mostly membrane-associated. In contrast, in Hb H disease of α-thalassaemia 1/Hb Constant Spring genotype the majority of inclusion bodies were in a floating stage. Possible mechanisms for the unexpected difference are discussed. 2018-10-12T07:36:41Z 2018-10-12T07:36:41Z 1983-01-01 Article Acta Haematologica. Vol.69, No.5 (1983), 314-318 10.1159/000206975 00015792 2-s2.0-0020698265 https://repository.li.mahidol.ac.th/handle/123456789/30534 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0020698265&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
A. Bunyaratvej
S. Sahaphong
N. Bhamarapravati
P. Wasi
Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
description Electron microscopic examination of intraerythrocytic inclusion bodies induced by methylene blue was carried out in 7 non-splenectomized patients with haemoglobin (Hb) H disease. In classical Hb H disease with the genotype of α-thalassaemia 1/α-thalassaemia 2 the inclusion bodies were mostly membrane-associated. In contrast, in Hb H disease of α-thalassaemia 1/Hb Constant Spring genotype the majority of inclusion bodies were in a floating stage. Possible mechanisms for the unexpected difference are discussed.
author2 Mahidol University
author_facet Mahidol University
A. Bunyaratvej
S. Sahaphong
N. Bhamarapravati
P. Wasi
format Article
author A. Bunyaratvej
S. Sahaphong
N. Bhamarapravati
P. Wasi
author_sort A. Bunyaratvej
title Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
title_short Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
title_full Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
title_fullStr Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
title_full_unstemmed Different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin H disease. An ultrastructural study
title_sort different patterns of intraerythrocytic inclusion body distribution in the two types of haemoglobin h disease. an ultrastructural study
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/30534
_version_ 1763490081186775040

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