Acute and subacute toxicity of piperine in mice, rats and hamsters

Piperine is acutely toxic to mice, rats and hamsters. The LD50values for a single i.V., i.p., s.c., i.g. and i.m. administration of piperine to adult male mice were 15.1, 43, 200, 330 and 400 mg/kg body wt, respectively. The i.p. LD50value was increased to 60 mg/kg body wt in adult female and 132 mg...

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Bibliographic Details
Main Authors: Pawinee Piyachaturawat, Thirayudh Glinsukon, Chaivat Toskulkao
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/30551
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Institution: Mahidol University