The combination of pivmecillinam and pivampicillin in the treatment of enteric fever

Thirty-nine patients with acute enteric fever received the fixed-dose oral combination of pivmecillinam/pivampicillin. Thirty-seven (95%) subjects responded satisfactorily. No relapses or persistent faecal excretion of salmonellae were seen in the 29 patients followed up for 2 to 19 weeks. The treat...

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Main Authors: D. Tanphaichitra, S. Srimuang, P. Chiaprasittigul, P. Menday, O. E. Christensen
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/30660
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spelling th-mahidol.306602018-10-12T14:42:33Z The combination of pivmecillinam and pivampicillin in the treatment of enteric fever D. Tanphaichitra S. Srimuang P. Chiaprasittigul P. Menday O. E. Christensen Mahidol University Leo Laboratories Limited Holbaek Sygehus Medicine Thirty-nine patients with acute enteric fever received the fixed-dose oral combination of pivmecillinam/pivampicillin. Thirty-seven (95%) subjects responded satisfactorily. No relapses or persistent faecal excretion of salmonellae were seen in the 29 patients followed up for 2 to 19 weeks. The treatment was well tolerated, no side-effects being recorded. In vitro studies revealed a synergistic interaction between mecillinam and ampicillin against isolates of Salmonella paratyphi A. © 1984 MMV Medizin Verlag GmbH München. 2018-10-12T07:42:33Z 2018-10-12T07:42:33Z 1984-11-01 Article Infection. Vol.12, No.6 (1984), 381-383 10.1007/BF01645219 14390973 03008126 2-s2.0-0021683977 https://repository.li.mahidol.ac.th/handle/123456789/30660 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021683977&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
D. Tanphaichitra
S. Srimuang
P. Chiaprasittigul
P. Menday
O. E. Christensen
The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
description Thirty-nine patients with acute enteric fever received the fixed-dose oral combination of pivmecillinam/pivampicillin. Thirty-seven (95%) subjects responded satisfactorily. No relapses or persistent faecal excretion of salmonellae were seen in the 29 patients followed up for 2 to 19 weeks. The treatment was well tolerated, no side-effects being recorded. In vitro studies revealed a synergistic interaction between mecillinam and ampicillin against isolates of Salmonella paratyphi A. © 1984 MMV Medizin Verlag GmbH München.
author2 Mahidol University
author_facet Mahidol University
D. Tanphaichitra
S. Srimuang
P. Chiaprasittigul
P. Menday
O. E. Christensen
format Article
author D. Tanphaichitra
S. Srimuang
P. Chiaprasittigul
P. Menday
O. E. Christensen
author_sort D. Tanphaichitra
title The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
title_short The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
title_full The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
title_fullStr The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
title_full_unstemmed The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
title_sort combination of pivmecillinam and pivampicillin in the treatment of enteric fever
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/30660
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