Pressor hyperresponsiveness in saline-infused rabbits

• Main Authors: Tetsuo Sakamaki, J. Alan Johnson, David W. Zeigler, Debra G. Koivunen, Suwan Siripaisarnpipat, Wayne L. Fowler, Charles G. Payne
• Other Authors: University of Missouri School of Medicine
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/30707
• Institution: Mahidol University

Conscious rabbits infused intravenously (i.v.) with isotonic saline at 1.5 to 1.8 ml/min for 24 hours had greater pressor responses to norepinephrine (NE) than did normal control rabbits. Infusion of the angiotensin II (ANGII) antagonist [Sar1, Ile8] ANGII did not decrease the exaggerated pressor re...