A potential role for interleukin‑33 and γ‑epithelium sodium channel in the pathogenesis of human malaria associated lung injury

• Main Authors: Sumate Ampawong, Urai Chaisri, Parnpen Viriyavejakul, Panote Prapansilp, Grau, Georges E, Turner, Gareth D. H., Emsri Pongponratn
• Other Authors: Mahidol University. Faculty of Tropical Medicine. Department of Tropical Pathology
• Format: Article
• Language: English
• Published: 2017
• Subjects: Open Access article; Aquaporin; Gamma-epithelial sodium channel; Interleukin-33; Leukocyte; Malaria; Pathogenesis; Plasmodium falciparum; Pulmonary oedema
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3080
• Institution: Mahidol University

Background: The pathogenesis of pulmonary oedema (PE) in patients with severe malaria is still unclear. It has been hypothesized that lung injury depends, in addition to microvascular obstruction, on an increased pulmonary capillary pressure and altered alveolar-capillary membrane permeability, ca...