Bone sparing effect of a novel phytoestrogen diarylheptanoid from Curcuma comosa Roxb. in ovariectomized rats

• Main Authors: Duangrat Tantikanlayaporn, Patsorn Wichit, Jittima Weerachayaphorn, Arthit Chairoungdua, Aporn Chuncharunee, Apichart Suksamrarn, Pawinee Piyachaturawat
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/30953

Phytoestrogens have been implicated in the prevention of bone loss in postmenopausal osteoporosis. Recently, an active phytoestrogen from Curcuma comosa Roxb, diarylheptanoid (DPHD), (3R)-1,7-diphenyl-(4 E,6E)-4,6-heptadien-3- ol, was found to strongly promote human osteoblast function in vitro. In...