Questions over high frequency of mutant PfATP6 haplotypes in traveller isolates

• Main Authors: Woodrow, Charles J, Gardner, Kate B, Bustamante, Leyla Y
• Other Authors: Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit (MORU)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Plasmodium falciparum, traveller isolates, PfATP6 A623E S769N haplotype, artemether resistance, Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3100
• Institution: Mahidol University

A recent paper in Malaria Journal suggests that a high proportion of Plasmodium falciparum isolates found in travellers returning from a range of African countries carry the PfATP6 A623E S769N haplotype, and that this genotype is associated with artemether resistance. Such a finding would represen...