Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger glucocorticoid response element-regulated gene expressi...

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Bibliographic Details
Main Authors: Ilse M. Beck, Zuzanna J. Drebert, Ruben Hoya-Arias, Ali A. Bahar, Michael Devos, Dorien Clarisse, Sofie Desmet, Nadia Bougarne, Bart Ruttens, Valerie Gossye, Geertrui Denecker, Sam Lievens, Marc Bracke, Jan Tavernier, Wim Declercq, Kris Gevaert, Wimden Van Berghe, Guy Haegeman, Karolien De Bosscher
Other Authors: Universiteit Gent
Format: Article
Published: 2018
Subjects:
Agricultural and Biological Sciences
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31002
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/31002

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