Third-stage Gnathostoma spinigerum larva excretory secretory antigens modulate function of Fc gamma receptor I-mediated monocytes in peripheral blood mononuclear cell culture

• Main Authors: Surachet Benjathummarak, Ratchanok Kumsiri, Supaporn Nuamtanong, Thareerat Kalambaheti, Jitra Waikagul, Nareerat Viseshakul, Yaowapa Maneerat
• Other Authors: Mahidol University. Faculty of Tropical Medicine. Department of Tropical Pathology
• Format: Article
• Language: English
• Published: 2017
• Subjects: Open Access article; Gnathostoma spinigerum; Excretory-secretory; FcγRI; Monocytes; Phagocytosis
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3102
• Institution: Mahidol University

Background: Third (infective)-stage Gnathostoma spinigerum larvae (L3) mainly cause human gnathostomiasis. G. spinigerum L3 migrate throughout the subcutaneous tissues, vital organs, and central nervous system and can cause various pathogenesis including sudden death. Interestingly, G. spinigerum...