Subpopulations of Staphylococcus aureus Clonal Complex 121 Are Associated with Distinct Clinical Entities

• Main Authors: Kevin Kurt, Jean Philippe Rasigade, Frederic Laurent, Richard V. Goering, Helena Žemličková, Ivana Machova, Marc J. Struelens, Andreas E. Zautner, Silva Holtfreter, Barbara Bröker, Stephen Ritchie, Sin Reaksmey, Direk Limmathurotsakul, Sharon J. Peacock, Christiane Cuny, Franziska Layer, Wolfgang Witte, Ulrich Nübel
• Other Authors: Robert Koch Institut
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31058
• Institution: Mahidol University

We investigated the population structure of Staphylococcus aureus clonal complex CC121 by mutation discovery at 115 genetic housekeeping loci from each of 154 isolates, sampled on five continents between 1953 and 2009. In addition, we pyro-sequenced the genomes from ten representative isolates. The...