Novel spiro-sesquiterpene from the mushroom Anthracophyllum sp. BCC18695

Novel spiro-sesquiterpene from the mushroom Anthracophyllum sp. BCC18695

novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinones A, C, axinysones A, and B. The relative...

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Bibliographic Details
Main Authors: Chakapong Intaraudom, Nattawut Boonyuen, Sumalee Supothina, Punsa Tobwor, Samran Prabpai, Palangpon Kongsaeree, Pattama Pittayakhajonwut
Other Authors: Thailand National Center for Genetic Engineering and Biotechnology
Format: Article
Published: 2018
Subjects:
Agricultural and Biological Sciences
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31118
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Institution: Mahidol University
Description
Summary:novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinones A, C, axinysones A, and B. The relative configuration of 1 and the hitherto unknown absolute stereochemistry of 3 were determined based on X-ray spectroscopic data. Biological activities including antimalarial activity against Plasmodium falciparum K1 strain, antibacterial property against Bacillus cereus, and cytotoxicity against MCF-7, KB, NCI-H187, and Vero cells of the isolated compounds were also evaluated. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

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