Viral quasispecies inference from 454 pyrosequencing

• Main Authors: Wan Ting Poh, Eryu Xia, Kwanrutai Chin-inmanu, Lai Ping Wong, Anthony Y. Cheng, Prida Malasit, Prapat Suriyaphol, Yik Ying Teo, Rick Twee Hee Ong
• Other Authors: National University of Singapore
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31143
• Institution: Mahidol University

Background: Many potentially life-threatening infectious viruses are highly mutable in nature. Characterizing the fittest variants within a quasispecies from infected patients is expected to allow unprecedented opportunities to investigate the relationship between quasispecies diversity and disease...