Selective FL quenching or enhancing of diimine ligands by guanine

• Main Authors: Srung Smanmoo, Shinya Kawasaki, Pramuan Tangboriboonrat, Takayuki Shibata, Tsutomu Kabashima, Masaaki Kai
• Other Authors: Thailand National Center for Genetic Engineering and Biotechnology
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31228
• Institution: Mahidol University

Diimine ligand (DL) 1 significantly exhibited the fluorescence quenching upon binding to guanine. Changing at the para-substituent of the phenyl ring from the hydroxyl to bromo groups reversely enhanced the fluorescence in the presence of guanine. The reverse in the fluorescence selectivity indicated the profound effect of the substituent at the para-position of the phenyl ring. The simple synthesis of DL 1 and DL 2 with good selectivity for guanine offers these DLs as promising compounds for chemosensors of other guanine derivatives. [Figure not available: see fulltext.] © 2013 Springer Science+Business Media New York.