A straightforward experimental approach to expression, purification, refolding, and enzymatic analysis of recombinant dengue virus NS2B(H)-NS3pro protease

Dengue virus threatens around 2.5 billion people worldwide; about 50 million become infected every year, and yet no vaccine or drug is available for prevention and/or treatment. The flaviviral NS2B-NS3pro complex is indispensable for flaviviral replication and is considered to be an important drug t...

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Bibliographic Details
Main Authors: M. Junaid, C. Angsuthanasombat, J. E.S. Wikberg, N. Ali, G. Katzenmeier
Other Authors: University of Malakand
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31260
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Institution: Mahidol University