An in vitro culture system for long-term expansion of epithelial and mesenchymal salivary gland cells: Role of TGF- β 1 in salivary gland epithelial and mesenchymal differentiation

• Main Authors: Kajohnkiart Janebodin, Worakanya Buranaphatthana, Nicholas Ieronimakis, Aislinn L. Hays, Morayma Reyes
• Other Authors: University of Washington, Seattle
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31277
• Institution: Mahidol University

Despite a pivotal role in salivary gland development, homeostasis, and disease, the role of salivary gland mesenchyme is not well understood. In this study, we used the Col1a1-GFP mouse model to characterize the salivary gland mesenchyme in vitro and in vivo. The Col1a1-GFP transgene was exclusively...