A heterodimer comprised of two bovine lactoferrin antimicrobial peptides exhibits powerful bactericidal activity against Burkholderia pseudomallei

• Main Authors: Aekkalak Puknun, Jan G M Bolscher, Kamran Nazmi, Enno C I Veerman, Sumalee Tungpradabkul, Surasakdi Wongratanacheewin, Sakawrat Kanthawong, Suwimol Taweechaisupapong
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31288
• Institution: Mahidol University

Melioidosis is a severe infectious disease that is endemic in Southeast Asia and Northern Australia. Burkholderia pseudomallei, the causative agent of this disease, has developed resistance to an increasing list of antibiotics, demanding a search for novel agents. Lactoferricin and lactoferrampin ar...