Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report
Diffuse parenchymal metastasis is an unusual pattern of liver metastasis that is capable of causing liver failure. In the present study, the authors describe malignant infiltration of the liver by primary breast carcinoma in an autopsy of a 49-year-old female who had a rapid onset of liver failure a...
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th-mahidol.313352018-10-19T12:27:25Z Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report Suchanan Hanamornroongruang Napakorn Sangchay Mahidol University Biochemistry, Genetics and Molecular Biology Medicine Diffuse parenchymal metastasis is an unusual pattern of liver metastasis that is capable of causing liver failure. In the present study, the authors describe malignant infiltration of the liver by primary breast carcinoma in an autopsy of a 49-year-old female who had a rapid onset of liver failure and died after three weeks. Ultrasonography and computed tomography (CT) scans of the abdomen, as well as macroscopic examination, failed to detect liver metastasis; while microscopic examination revealed diffuse tumor cells with a loss of E-cadherin expression infiltrating into the liver parenchyma. The prognosis of liver failure associated with malignant infiltration is extremely poor; the survival time of patients is extremely low. Liver biopsy may be the most efficient technique for confirming the diagnosis during the patient's life. 2018-10-19T04:40:18Z 2018-10-19T04:40:18Z 2013-04-01 Article Oncology Letters. Vol.5, No.4 (2013), 1250-1252 10.3892/ol.2013.1165 17921082 17921074 2-s2.0-84874418767 https://repository.li.mahidol.ac.th/handle/123456789/31335 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84874418767&origin=inward |
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Biochemistry, Genetics and Molecular Biology Medicine Suchanan Hanamornroongruang Napakorn Sangchay Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
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Diffuse parenchymal metastasis is an unusual pattern of liver metastasis that is capable of causing liver failure. In the present study, the authors describe malignant infiltration of the liver by primary breast carcinoma in an autopsy of a 49-year-old female who had a rapid onset of liver failure and died after three weeks. Ultrasonography and computed tomography (CT) scans of the abdomen, as well as macroscopic examination, failed to detect liver metastasis; while microscopic examination revealed diffuse tumor cells with a loss of E-cadherin expression infiltrating into the liver parenchyma. The prognosis of liver failure associated with malignant infiltration is extremely poor; the survival time of patients is extremely low. Liver biopsy may be the most efficient technique for confirming the diagnosis during the patient's life. |
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Mahidol University |
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Mahidol University Suchanan Hanamornroongruang Napakorn Sangchay |
format |
Article |
author |
Suchanan Hanamornroongruang Napakorn Sangchay |
author_sort |
Suchanan Hanamornroongruang |
title |
Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
title_short |
Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
title_full |
Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
title_fullStr |
Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
title_full_unstemmed |
Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report |
title_sort |
acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: a case report |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/31335 |
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1763488575991578624 |