Short report: Molecular confirmation of co-infection by pathogenic leptospira spp. and orientia tsutsugamushi in patients with acute febrile illness in Thailand

• Main Authors: Piengchan Sonthayanon, Wirongrong Chierakul, Vanaporn Wuthiekanun, Direk Limmathurotsakul, Premjit Amornchai, Lee D. Smythe, Nicholas P. Day, Sharon J. Peacock
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31865

Leptospirosis and scrub typhus are major causes of acute febrile illness in rural Asia, where co-infection is reported to occur based on serologic evidence. We re-examined whether co-infection occurs by using a molecular approach. A duplex real-time polymerase chain reaction was developed that targe...