Comparative assessment of the intracellular survival of the Burkholderia pseudomallei bopC mutant

• Main Authors: Varintip Srinon, Sunsiree Muangman, Nithima Imyaem, Veerachat Muangsombut, Natalie R. Lazar Adler, Edouard E. Galyov, Sunee Korbsrisate
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/31890

Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative saprophytic bacterium capable of surviving within phagocytic cells. To assess the role of BopC (a type III secreted effector protein) in the pathogenesis of B. pseudomallei, a B. pseudomallei bopC mutant was used to in...