Serotype-Specific Changes in Invasive Pneumococcal Disease after Pneumococcal Conjugate Vaccine Introduction: A Pooled Analysis of Multiple Surveillance Sites

• Main Authors: Daniel R. Feikin, Eunice W. Kagucia, Jennifer D. Loo, Ruth Link-Gelles, Milo A. Puhan, Thomas Cherian, Orin S. Levine, Cynthia G. Whitney, Katherine L. O'Brien, Matthew R. Moore, Richard A. Adegbola, Mary Agocs, Krow Ampofo, Nick Andrews, Theresa Barton, Javier Benito, Claire V. Broome, Michael G. Bruce, Lisa R. Bulkow, Carrie L. Byington, Teresa Camou, Heather Cook, Suzanne Cotter, Ron Dagan, Philippe de Wals, Geneviève Deceuninck, Barbara Denham, Giles Edwards, Juhani Eskola, Margaret Fitzgerald, Emmanouil Galanakis, Gabriela Garcia-Gabarrot, Juan J. Garcia-Garcia, Amadeu Gene, Borja Gomez, Helen Heffernan, Thomas W. Hennessy, Sigrid Heuberger, Markus Hilty, Helene Ingels, Sanjay Jayasinghe, James D. Kellner, Nicola P. Klein, Andrea Kormann-Klement, Jana Kozakova, Vicki Krause, Paula Kriz, Lotte Lambertsen, Agnès Lepoutre, Marc Lipsitch, Mariana Lopez-Vega, Marguerite Lovgren, Sofia Maraki, Edward O. Mason, Peter B. McIntyre, Robert Menzies, Allison Messina, Elizabeth Miller, Santiago Mintegi, Jitka Motlova, Lawrence H. Moulton, Kathrin Mühlemann, Carmen Muñoz-Almagro, David R. Murdoch, Daniel E. Park, Arthur L. Reingold, Raquel Sa-Leao, Abanti Sanyal, Peter G. Smith, Lodewijk Spanjaard, Chonnamet Techasaensiri, Richard E. Thompson, Koh C. Thoon, Gregory J. Tyrrell, Palle Valentiner-Branth, Arie van der Ende, Otto G. Vanderkooi, Mark P.G. van der Linden, Emmanuelle Varon, Jan Verhaegen, Didrik F. Vestrheim, Imelda Vickers, Anne von Gottberg, Rüdiger von Kries, Pauline Waight, Robert Weatherholtz, Susanne Weiss, Arnold Yee, Anita K.M. Zaidi
• Other Authors: Johns Hopkins Bloomberg School of Public Health
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/32199
• Institution: Mahidol University

Background:Vaccine-serotype (VT) invasive pneumococcal disease (IPD) rates declined substantially following introduction of 7-valent pneumococcal conjugate vaccine (PCV7) into national immunization programs. Increases in non-vaccine-serotype (NVT) IPD rates occurred in some sites, presumably represe...