Comparison of gastrointestinal adverse effects between cyclooxygenase-2 inhibitors and non-selective, non-steroidal anti-inflammatory drugs plus proton pump inhibitors: A systematic review and meta-analysis

• Main Authors: Saharat Jarupongprapa, Prapassorn Ussavasodhi, Wanruchada Katchamart
• Other Authors: Nakornprathom Hospital
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/32276
• Institution: Mahidol University

Background: There are conflicting and inconsistent data regarding the gastrointestinal (GI) protective effect of cyclooxygenase-2 (COX-2) inhibitors and of non-steroidal anti-inflammatory drugs (NSAIDs) plus proton-pump inhibitors (PPI). Aim: To compare the adverse GI effects between COX-2 inhibitor...