High plasma efavirenz concentration and CYP2B6 polymorphisms in Thai HIV-1 infections

High plasma efavirenz concentration and CYP2B6 polymorphisms in Thai HIV-1 infections

Efavirenz is mainly metabolized by cytochrome P450 2B6 (CYP2B6). This study aimed to examine the frequencies of CYP2B6 and the association between CYP2B6 polymorphisms and plasma efavirenz concentrations in an HIV-1 infected Thai population. Mid-dose plasma efavirenz concentration was determined at...

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Bibliographic Details
Main Authors: Chonlaphat Sukasem, Montri Chamnanphon, Napatrupron Koomdee, Apichaya Puangpetch, Siwalee Santon, Thawinee Jantararoungtong, Santirat Prommas, Wasun Chantratita, Weerawat Manosuthi
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/32672
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Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/32672

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