Precipitation-lyophilization-homogenization (PLH) for preparation of clarithromycin nanocrystals: Influencing factors on physicochemical properties and stability

Nanocrystals is one of effective technologies used to improve solubility and dissolution behavior of poorly soluble drugs. Clarithromycin is classified in BCS class II having low bioavailability due to very low dissolution behavior. The main purpose of this study was to investigate an efficiency of...

Full description

Saved in:
Bibliographic Details
Main Authors: Boontida Morakul, Jiraphong Suksiriworapong, Jiraporn Leanpolchareanchai, Varaporn Buraphacheep Junyaprasert
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/32727
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University