Novel identification of Dermacentor variabilis Arp2/3 complex and its role in rickettsial infection of the arthropod vector

• Main Authors: Natthida Petchampai, Piyanate Sunyakumthorn, Mark L. Guillotte, Victoria I. Verhoeve, Kaikhushroo H. Banajee, Michael T. Kearney, Kevin R. Macaluso
• Other Authors: Louisiana State University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33023
• Institution: Mahidol University

Tick-borne spotted fever group (SFG) Rickettsia species must be able to infect both vertebrate and arthropod host cells. The host actin-related protein 2/3 (Arp2/3) complex is important in the invasion process and actin-based motility for several intracellular bacteria, including SFG Rickettsia in D...