Clinical and laboratory update on the DEL variant

• Main Authors: Pornlada Nuchnoi, Jairak Thongbus, Apapan Srisarin, Usanee Kerdpin, Virapong Prachayasittikul
• Other Authors: Mahidol University
• Format: Review
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33211

Serological assays for the RhD blood group are based on detection of the RhD antigen on human red blood cells using a specific anti-D antibody. The weak expression of the RhD antigen in the DEL variant hinders the sensitivity of conventional serological assays. Evidence of anti-D immunization in pat...