Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

© The Author(s) 2014. Short-wave ultraviolet light induces both mildly helixdistorting cyclobutane pyrimidine dimers (CPDs) and severely distorting (6-4) pyrimidine pyrimidone photoproducts ((6-4)PPs). The only DNA polymerase (Pol) that is known to replicate efficiently across CPDs is Polη, a member...

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Bibliographic Details
Main Authors: Jacob G. Jansen, Piya Temviriyanukul, Niek Wit, Frédéric Delbos, Claude Agnès Reynaud, Heinz Jacobs, Niels D. Wind
Other Authors: Leiden University Medical Center - LUMC
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/33249
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Institution: Mahidol University