The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis

• Main Authors: Sariqa Wagley, Claudia Hemsley, Rachael Thomas, Madeleine G. Moule, Muthita Vanaporn, Clio Andreae, Matthew Robinson, Stan Goldman, Brendan W. Wren, Clive S. Butler, Richard W. Titball
• Other Authors: University of Exeter
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33423
• Institution: Mahidol University

The twin arginine translocation (Tat) system in bacteria is responsible for transporting folded proteins across the cytoplasmic membrane, and in some bacteria, Tat-exported substrates have been linked to virulence. We report here that the Tat machinery is present in Burkholderia pseudomallei, B. mal...