Folic acid-modified methotrexate-conjugated PEGylated poly(ε- caprolactone) nanoparticles for targeted delivery
Functionalized nanoparticles of polymer-drug conjugates of PEGylated poly(ε-caprolactone) (PEGylated P(CL)) with methotrexate (MTX) and folic acid (FOL) were developed and investigated for their targeting efficiency. FOL- and MTX-conjugated PEGylated P(CL) copolymers were employed to prepare P(MTXCL...
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Main Authors: | , , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/33574 |
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Institution: | Mahidol University |