Folic acid-modified methotrexate-conjugated PEGylated poly(ε- caprolactone) nanoparticles for targeted delivery

Functionalized nanoparticles of polymer-drug conjugates of PEGylated poly(ε-caprolactone) (PEGylated P(CL)) with methotrexate (MTX) and folic acid (FOL) were developed and investigated for their targeting efficiency. FOL- and MTX-conjugated PEGylated P(CL) copolymers were employed to prepare P(MTXCL...

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Bibliographic Details
Main Authors: Ousanee Issarachot, Jiraphong Suksiriworapong, Mikihisa Takano, Ryoko Yumoto, Varaporn Buraphacheep Junyaprasert
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/33574
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Institution: Mahidol University