Illuminating the origins of spectral properties of green fluorescent proteins via proteochemometric and molecular modeling

• Main Authors: Chanin Nantasenamat, Saw Simeon, Wiwat Owasirikul, Napat Songtawee, Maris Lapins, Virapong Prachayasittikul, Jarl E.S. Wikberg
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Chemistry; Mathematics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33612

© 2014 Wiley Periodicals, Inc. Green fluorescent protein (GFP) has immense utility in biomedical imaging owing to its autofluorescent nature. In efforts to broaden the spectral diversity of GFP, there have been several reports of engineered mutants via rational design and random mutagenesis. Underst...