Insights into antioxidant activity of 1-adamantylthiopyridine analogs using multiple linear regression

• Main Authors: Apilak Worachartcheewan, Chanin Nantasenamat, Wiwat Owasirikul, Teerawat Monnor, Orapan Naruepantawart, Sayamon Janyapaisarn, Supaluk Prachayasittikul, Virapong Prachayasittikul
• 其他作者: Mahidol University
• 格式: Article
• 出版: 2018
• 主題: Chemistry; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/33634

A data set of 1-adamantylthiopyridine analogs (1-19) with antioxidant activity, comprising of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide dismutase (SOD) activities, was used for constructing quantitative structure-activity relationship (QSAR) models. Molecular structures were geometrically...